Jaw bone created from stem cells - case study

Scientists have created part of the jaw joint in the lab using human adult stem cells. They say it is the first time a complex, anatomically-sized bone has been accurately created in this way. It is hoped the technique could be used not only to treat disorders of the specific joint, but more widely to correct problems with other bones too. The Columbia University study appears in Proceedings of the National Academy of Sciences. The bone which has been created in the lab is known as the temporomandibular joint (TMJ).

Problems with the joint can be the result of birth defects, arthritis or injury. Although they are widespread, treatment can be difficult. The joint has a complex structure which makes it difficult to repair by using grafts from bones elsewhere in the body. BBC.co.uk 10th October 2009

Problems with joints and bones can be the result of birth defects, arthritis or injury. Although they are widespread, treatment can be difficult.

Successful treatments and therapies to grow bones or joints is one of the latest uses for stem cells. The latest study used human stem cells taken from bone marrow. The cells are cultured using a specially-designed bioreactor which infuses growing tissue with nutrients found during natural bone development..

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